Valvular heart diseaseIncidence, Imaging Analysis, and Early and Late Outcomes of Stroke After Cardiac Valve Operation
Section snippets
Methods
The protocol was approved by our local institutional review board and compliant to the Health Insurance Portability and Accountability Act regulations and the ethical guidelines of the 1975 Declaration of Helsinki. Approval included a waiver of informed consent.
From January 1, 1998, to December 31, 2006, 2,808 patients underwent valve surgery with or without concomitant CABG procedures at The Mount Sinai Hospital. Clinical variables were prospectively entered into the New York State Department
Results
A total of 2,808 adult patients were included in the study. Mean age was 63 ± 15 years and 55% of patients (n = 1,610) were men. Patient demographics and preoperative risk factors are listed in Table 1. Distribution of valve procedures was aortic valve replacement (29%, n = 820), mitral valve reconstruction (30%, n = 855), mitral valve replacement (12%, n = 323), combined aortic valve replacement and mitral valve reconstruction (5%, n = 143), combined aortic and mitral valve replacement (4%, n
Discussion
Our study was designed to examine the issue of stroke in a large cohort of patients undergoing valvular surgery. In our analysis, using a precise definition of stroke based on the New York State Department of Health (any new permanent focal neurologic deficit), overall incidence of this complication was 2.2%. A notable finding was that valve pathology did not influence the incidence of stroke, which was similar between different types of single-valve operations. However, rate of stroke was
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