Comparison of cardiovascular and skeletal features of primary mitral valve prolapse and Marfan syndrome☆
References (30)
- et al.
Thoracic skeletal abnormalities in idiopathic mitral valve prolapse
Am J Cardiol
(1975) - et al.
Incidence of mitral valve prolapse in subjects with thoracic skeletal abnormalities—a prospective study
Am Heart J
(1979) - et al.
Relationship between clinical features of the mitral prolapse syndrome and echocardiographically documented mitral valve prolapse
JACC
(1986) - et al.
Skeletal abnormalities in mitral valve prolapse
Clin Radiol
(1983) - et al.
Echocardiography in Marfan's syndrome
Chest
(1976) - et al.
Echocardiographic assessment of cardiovascular abnormalities in the Marfan syndrome. Comparison with clinical findings and with roentgenographic estimation of aortic root size
Am J Med
(1983) - et al.
Mitral valve dysfunction in the Marfan syndrome. Clinical and echocardiographic study of prevalence and natural history
Am J Med
(1983) - et al.
Indices of relative body weight and ideal body weight charts
J Chronic Dis
(1984) - et al.
Diagnosis and classification of severity of mitral valve prolapse: methodologic, biologic and prognostic considerations
Am Heart J
(1987) - et al.
Distinctive anthropometric characteristics of women with mitral valve prolapse
Am J Med
(1981)
Increased left ventricular mass in idiopathic mitral valve prolapse
Chest
Symptomatic valvular myxomatous transformation (the floppy valve syndrome). A possible “forme fruste” of the Marfan syndrome
Circulation
Familial syndrome of midsystolic click and late systolic murmur
Br Heart J
Radiographic appearance of the thorax in systolic click-late systolic murmur syndrome
Am J Cardiol
Aortic root dilatation and mitral valve prolapse in the Marfan syndrome
Circulation
Cited by (82)
ACR Appropriateness Criteria® Congenital or Acquired Heart Disease
2023, Journal of the American College of RadiologyArrhythmogenic Mitral Valve Prolapse and Sudden Cardiac Death: An Update and Current Perspectives
2023, Current Problems in CardiologyAssociation between pectus excavatum and congenital genetic disorders: A systematic review and practical guide for the treating physician
2021, Journal of Pediatric SurgeryCitation Excerpt :Following eligibility assessment, 119 full text articles were included in the systematic review (Fig. 1). Study characteristics are presented in Table 1 [17–137] and more detailed study chracteristics are presented in Appendix C. Sixteen uncontrolled cohort studies, 46 case series and 57 case reports have been included, representing 20 different congenital genetic disorders and 487 patients with PE and an underlying genetic disorder. Genetic disorders have been diagnosed through either genetic molecular analysis (n = 51 studies) or clinical features and family history (n = 23 studies).
Mitral Valve Prolapse: Multimodality Imaging and Genetic Insights
2017, Progress in Cardiovascular DiseasesCitation Excerpt :Non-syndromic MVP can be familial or sporadic. Syndromic MVP occurs in association with connective tissue disorders such as Marfan syndrome, Loeys-Dietz syndrome, Ehler-Danlos syndrome, osteogenesis imperfecta, Pseudoxanthoma Elasticum and aneurysms of osteoarthritis syndrome.12–16 Based on intraoperative findings and histological phenotype, degenerative MV disease has also been classified into two distinct entities in the surgical literature: Barlow's disease (BD) and fibro-elastic deficiency (FED).17
Mitral valve prolapse syndrome and MASS phenotype: Stability of aortic dilatation but progression of mitral valve prolapse
2016, IJC Heart and VasculatureCitation Excerpt :The risk for MV surgery depended exclusively on the presence of classical echocardiographic predictors of MV disease progression such as LV diameters and MV dysfunction at baseline. The diagnostic criteria of MVPS and MASS underwent substantial changes since their initial description [11,17,37]. These changes may be explained by a combination of factors that have significantly evolved over time: molecular testing has become more widely available and now plays a more important role in the new nosology as compared with the initial Berlin nosology [10,38], more reliable 2D echocardiography has replaced the former M-mode echocardiography to diagnose MVP [39], and new entities such as the Loeys–Dietz syndrome caused by TGFBR1 or TGFBR2 mutations have been added to the phenotypic spectrum of Marfan-like syndromes [40].
The Expanding Clinical Spectrum of Extracardiovascular and Cardiovascular Manifestations of Heritable Thoracic Aortic Aneurysm and Dissection
2016, Canadian Journal of CardiologyCitation Excerpt :Myocardial dysfunction in children with severe MFS is well described,23,24 but again this is in the setting of severe valvular regurgitation and ventricular volume overload in neonatal life and potentially during fetal development. Mild impairment of myocardial function independent of valvular and aortic involvement likely exists in some individuals with MFS and ventricular functional assessment should be part of routine long-term follow-up.27-39 Additionally, a relationship between a specific genotype in MFS with a nonmissense FBN1 mutation and left ventricular dilatation has been recently reported.40
- ☆
This study was supported in part by grant HL 22006 from the National Heart, Lung, and Blood Institute, Bethesda, Maryland.