2011 (n=7696) | 2015 (n=8111) | P value | |
Demographics | |||
Age (years) | 65 (55–75) | 65 (55–74) | 0.9 |
Women | 2247 (29.2) | 2311 (28.5) | 0.3 |
Cardiovascular risk factors | |||
Hypertension | 3890 (50.5) | 4197 (51.7) | 0.1 |
Diabetes | 1558 (20.2) | 1818 (22.4) | 0.0009 |
Dyslipidaemia | 4843 (62.9) | 6452 (79.5) | <0.0001 |
Current smoker | 2854 (37.1) | 2853 (35.2) | 0.01 |
Clustering of risk factors | |||
≥3 | 1612 (20.9) | 2027 (25) | <0.0001 |
2 | 2878 (37.4) | 3360 (41.4) | <0.0001 |
1 | 2357 (30.6) | 2275 (28) | 0.0004 |
None | 849 (11) | 449 (5.5) | <0.0001 |
Medical history | |||
Myocardial infarction | 814 (10.6) | 569 (7) | <0.0001 |
Coronary heart disease | 1568 (20.4) | 1897 (23.4) | <0.0001 |
PCI | 180 (2.3) | 251 (3.1) | 0.004 |
Coronary artery bypass graft | 21 (0.3) | 14 (0.2) | 0.2 |
Stroke | 897 (11.7) | 1022 (12.6) | 0.07 |
Clinical characteristics | |||
Symptom onset to admission (hours) | 12 (3–72) | 24 (4–96) | <0.0001 |
Chest discomfort | 7118 (92.5) | 7478 (92.2) | 0.5 |
Left bundle branch block | 97 (1.3) | 65 (0.8) | 0.004 |
Cardiac arrest | 125 (1.6) | 104 (1.3) | 0.07 |
Cardiogenic shock | 508 (6.6) | 630 (7.8) | 0.005 |
Acute stroke | 83 (1.1) | 217 (2.7) | <0.0001 |
Heart rate (beats per minute) | |||
<50 | 384 (5) | 306 (3.8) | 0.0002 |
50–110 | 6917 (89.9) | 7278 (89.7) | 0.8 |
>110 | 395 (5.1) | 527 (6.5) | 0.0003 |
Heart rate | 76 (65–89.5) | 78 (66–90) | 0.0009 |
Systolic blood pressure (mm Hg) | |||
<90 | 408 (5.3) | 430 (5.3) | >0.9 |
90–139 | 4658 (60.5) | 5017 (61.9) | 0.09 |
≥140 | 2630 (34.2) | 2664 (32.8) | 0.08 |
Mini-GRACE risk score | 142 (122–160) | 141 (120–160) | 0.06 |
Data are median (IQR) or n (%), for which n is the number of patients in the study sample and % is a nationally representative rate.
GRACE, Global Registry of Acute Coronary Events; PCI, percutaneous coronary intervention; STEMI, ST segment elevation myocardial infarction.