Table 3

Clinical and echocardiographic correlates of discordant grading moderate AS

Univariate analysisMultivariate analysis
Odds ratio (95% CI)P valueOdds ratio (95% CI)P value
Age (per 1 year increase)1.04 (1.02 to 1.05)<0.0011.03 (1.01 to 1.06)0.006
Male1.40 (0.98 to 2.01)0.066
Coronary artery disease (yes/no)2.94 (2.01 to 4.31)<0.0011.74 (1.04 to 2.89)0.034
Previous MI (yes/no)3.08 (2.02 to 4.70)<0.0011.44 (0.82 to 2.53)0.207
LVEDV (per unit increase)1.01 (1.00 to 1.01)0.0061.00 (0.99 to 1.00)0.368
LVEF (per unit increase)0.93 (0.92 to 0.94)<0.0010.96 (0.94 to 0.98)<0.001
LV mass index (per unit increase)1.00 (1.00 to 1.01)0.094
Moderate/severe MR (yes/no)2.45 (1.41 to 4.24)0.0011.56 (0.71 to 3.40)0.265
Stroke volume index (per unit increase)0.88 (0.86 to 0.90)<0.0010.90 (0.88 to 0.92)<0.001
Atrial fibrillation (yes/no)1.64 (1.12 to 2.40)0.0111.20 (0.73 to 1.98)0.472
  • AS, aortic stenosis; LV, left ventricular; LVEDV, left ventricular end-diastolic volume; LVEF, left ventricular ejection fraction; MI, myocardial infarction; MR, mitral regurgitation.