Multivariate COX regression analysis of factors associated with all-cause mortality in young (aged <50) compared with older (aged ≥50) patients with STEMI treated with PPCI
| Age <50 | Age ≥50 | |||
| Adjusted HR (95% CI) | P value | Adjusted HR (95% CI) | P value | |
| Age, per 1 year increase | 0.93 (0.85–1.02) | 0.134 | 1.05 (1.03–1.07) | <0.0001 |
| Female gender | 1.34 (0.29–7.97) | 0.667 | 0.63 (0.41–0.97) | 0.037 |
| Indian ethnicity | 0.83 (0.25–2.55) | 0.756 | 1.47 (0.97–2.23) | 0.070 |
| Current smoker | 0.74 (0.31–2.43) | 0.567 | 0.78 (0.54–1.12) | 0.185 |
| Hypertension | 0.61 (0.16–2.05) | 0.467 | 1.01 (0.71–1.44) | 0.939 |
| Diabetes mellitus | 2.77 (0.90–8.53) | 0.077 | 1.31 (0.95–1.89) | 0.102 |
| Dyslipidaemia | 0.46 (0.12–1.49) | 0.235 | 1.02 (0.73–1.42) | 0.911 |
| Family history of IHD | 0.20 (0.03–1.62) | 0.133 | 0.60 (0.28–1.29) | 0.191 |
| Previous AMI | 1.48 (0.24–8.33) | 0.672 | 0.74 (0.48–1.14) | 0.172 |
| Previous stroke | 19.17 (2.69–85.68) | 0.003 | 1.24 (0.75–2.04) | 0.409 |
| Chronic kidney disease | 0.05 (0.01–72.23) | 0.987 | 2.58 (1.73–3.81) | <0.0001 |
| Atrial fibrillation | 0.05 (0.01–42.67) | 0.997 | 1.18 (0.58–2.43) | 0.649 |
| DTBT ≥90 min | 5.42 (1.97–14.93) | 0.001 | 2.07 (1.51–2.84) | <0.0001 |
| Multivessel disease | 3.21 (1.13–9.08) | 0.028 | 1.06 (0.78–1.43) | 0.720 |
AMI, acute myocardial infarction; DTBT, door to balloon time; IHD, ischaemic heart disease; PPCI, primary percutaneous coronary intervention; STEMI, ST segment elevation myocardial infarction.