Table 4

Univariate and multivariate Cox analyses for major adverse cardiac events (A) and arrhythmic events (B) in patients with atrial fibrillation according to the periodontitis at 18-month follow-up.

Variable
N (%)
Univariate analysisMultivariate analysis
OR (95% CI)P valuesOR (95% CI)P values
(A) Major adverse cardiac events
 Periodontitis17.532 (7.330 to 41.937)<0.00117.776 (3.459 to 91.344)0.001
 CHA2DS2-VASc1.280 (1.010 to 1.622)0.041
 HAS-BLED2.119 (1.590 to 2.825)<0.001
 LAVi1.030 (1.007 to 1.054)0.012
 E/E′1.060 (1.060 to 1.118)0.029
 WBC counts1.000 (0.998 to 1.000)0.588
 NLR1.014 (0.980 to 1.051)0.420
 hsCRP0.065 (0.001 to 7.037)0.253
(B) Arrhythmic events
 Periodontitis40.688 (11.780 to 140.533)<0.0019.185 (1.241 to 67.964)0.030
 CHA2DS2-VASc1.434 (1.089 to 1.888)0.010
 HAS-BLED3.608 (2.242 to 5.805)<0.001
 LAVi1.107 (1.064 to 1.151)<0.0011.055 (1.009 to 1.103)0.019
 E′1.113 (1.041 to 1.191)0.002
 WBC count1.000 (1.000 to 1.001)0.011
 NLR1.102 (1.003 to 1.169)0.006
  • E, the peak mitral flow velocity of the early rapid filling wave; E′, early diastolic mitral annulus velocity; hsCRP, high-sensitive C-reactive protein; LAVi, left atrial volume index; NLR, neutrophil/lymphocyte ratio; WBC, white blood cell count.