Table 3A

Survival analysis of sST2 and galectin-3 as continuous variables for all-cause mortality and cardiac mortality

All-cause mortalityP valueCardiac mortalityP value
HR (95% CI)HR (95% CI)
sST2 main group
 Univariate1.05 (1.03 to 1.07)<0.0011.03 (1.00 to 1.06)0.040
 Multivariate1.04 (1.02 to 1.07)0.003
sST2 subgroups
 Idiopathic DCM1.04 (1.01 to 1.07)0.0191.02 (0.98 to 1.07)0.394
 DCMi⋎viral1.10 (1.05 to 1.17)<0.0011.10 (1.02 to 1.18)0.013
 fDCM1.04 (1.00 to 1.09)0.0521.02 (0.95 to 1.09)0.646
Galectin-3 main group
 Univariate1.03 (0.91 to 1.17)0.6481.01 (0.87 to 1.16)0.944
 Multivariate1.04 (0.92 to 1.18)0.562
Galectin-3 subgroups
 Idiopathic DCM1.06 (0.86 to 1.30)0.5811.03 (0.83 to 1.30)0.766
 DCMi⋎viral1.06 (0.86 to 1.31)0.5870.98 (0.74 to 1.29)0.876
 fDCM0.96 (0.76 to 1.21)0.7160.99 (0.77 to 1.28)0.945
  • Main group: n=262, idiopathic DCM: n=117, DCMi⋎viral: n=87, fDCM: n=58.

  • Multivariate model adjusted for sex, age, body mass index, diabetes mellitus, aetiology, QRS duration, New York Heart Association class, left ventricular ejection fraction, left ventricular end diastolic diameter.

  • DCM, dilated cardiomyopathy; DCMi⋎viral, inflammatory and/or viral DCM; fDCM, familial DCM.