Clinical characteristics and ECG data
| Baseline visit | Follow-up visit | P value | |
| Height (cm) | 174±11 | 174±11 | 0.67 |
| Weight (kg) | 76±16 | 76±16 | 0.42 |
| Body mass index (kg/m2) | 25±3 | 25±3 | 0.43 |
| Age (years) | 54±8 | 58±8 | <0.01 |
| Systolic blood pressure (mm Hg) | 119±10 | 126±9 | <0.001 |
| Diastolic blood pressure (mm Hg) | 73±10 | 83±8 | <0.001 |
| ECG parameters | |||
| Heart rate (1/min) | 67±9 | 62±6 | <0.01 |
| PQ (ms) | 158±25 | 163±25 | 0.06 |
| QRS (ms) | 98±10 | 95±7 | 0.1 |
| QTc (ms) | 398±12 | 405±10 | 0.05 |
Continuous data were expressed as mean±SD.