Demographic, clinical, microbiology and echocardiographic characteristics of patients with definite endocarditis according to study period
| Variable | Pre-ET (n=101) | Post-ET (n=95) | P value |
| Age (years) | 56.1±14.4 | 57.5±17.5 | 0.54 |
| Male | 67 (66.3) | 73 (76.8) | 0.12 |
| Diabetes mellitus | 14 (13.9) | 15 (15.8) | 0.84 |
| EuroSCORE II | 11.7±10.6 | 13.1±10.3 | 0.35 |
| Biochemical results* | |||
| Serum eGFR (mL/min) | 66.8±26.1 | 66.3±25.1 | 0.91 |
| Serum haemoglobin (g/dL) | 91.5±32.7 | 89.6±32.2 | 0.70 |
| Serum neutrophils (x109/L) | 9.1±5.3 | 8.2±5.1 | 0.23 |
| Serum CRP (mg/L) | 93.4±66.1 | 105.5±90.5 | 0.29 |
| Predisposing conditions for IE | |||
| Predisposing cardiac disease† | 30 (29.7) | 26 (27.4) | 0.75 |
| Intravenous drug abuse | 10 (9.9) | 9 (9.5) | 1.00 |
| History of IE | 10 (9.9) | 9 (9.5) | 1.00 |
| Intervention (12 months)‡ | 21 (20.8) | 14 (14.7) | 0.35 |
| Localisation of vegetation | |||
| AV | 39 (38.6) | 38 (40.0) | 0.96 |
| AV+aortic root | 9 (8.9) | 8 (8.4) | |
| MV | 29 (28.7) | 27 (28.4) | |
| AV+MV | 7 (6.9) | 8 (8.4) | |
| TV | 11 (10.9) | 8 (8.4) | |
| AV+MV+TV | 2 (2) | 3 (3.2) | |
| Pacemaker lead (no valve) | 1 (1) | 2 (2.1) | |
| No vegetation identified | 3 (3.0) | 1 (1.1) | |
| Valve type | |||
| Native | 71 (70.3) | 68 (71.6) | 1.00 |
| Prosthetic | 22 (21.8) | 22 (23.2) | |
| Native and prosthetic | 4 (4.0) | 2 (2.1) | |
| Microbiology | |||
| Blood culture positive | 82 (81.2) | 85 (89.5) | 0.11 |
| Viridans group streptococci | 14 (13.9) | 9 (9.5) | 0.50 |
| Streptococcus gallolyticus | 6 (5.9)s3 (3.2) | ||
| Staphylococcus aureus | 24 (23.8) | 27 (28.4) | |
| Enterococci | 9 (8.9) | 11 (11.6) |
Data shown as mean±SD or number (percentage).
*Admission values.
†Rheumatic disease, prosthetic valve or valve repair.
‡Dental or surgical interventions within the past 12 months.
AV, aortic valve; CRP, C-reactive protein; eGFR, estimated glomerular filtration rate; ET, endocarditis team; EuroSCORE, European System for Cardiac Operative Risk Evaluation; IE, infective endocarditis; MV, mitral valve; TV, tricuspid valve.