Management and outcome data of patients with definite endocarditis according to study period
| Variable | Pre-ET (n=101) | Post-ET (n=95) | P value | Post-ET (Pre-ET involvement)* |
| Complications | ||||
| Immunological phenomena | 11 (10.9) | 11 (11.6) | 1.00 | 9 (81.8) |
| Acute stroke | 22 (21.8) | 19 (20.0) | 0.86 | 11 (57.9) |
| Other emboli | 38 (37.6) | 31 (32.6) | 0.55 | 16 (51.6) |
| Congestive cardiac failure | 17 (16.8) | 15 (15.8) | 1.00 | 4 (26.7) |
| Uncontrolled sepsis | 18 (17.8) | 27 (28.4) | 0.09 | 8 (29.6) |
| Valvular abscess | 11 (10.9) | 13 (13.6) | 0.66 | 8 (61.5) |
| Renal failure† | 11 (10.9) | 10 (10.5) | 1.00 | 5 (50.0) |
| Investigations | ||||
| Time to first TTE (days) | 7.8±11.6 | 4.8±7.9 | 0.04 | |
| Time to TOE following TTE (days) | 4.9±4.1 | 3.5±3.1 | 0.02 | |
| Number of patients undergoing TOE | 69 (68.3) | 77 (81.1) | 0.05 | |
| Management | ||||
| Time to IE-specific antibiotics | 4.0±4.0 | 2.5±3.2 | 0.004 | |
| Duration of stay | 29.2+15.9 | 23.9±15.6 | 0.02 | |
| Management strategy | ||||
| Medical | 21 (20.8) | 24 (25.3) | 0.55 | |
| Medical (surgical turndown) | 6 (5.9) | 8 (8.4) | ||
| Surgical | 74 (73.3) | 63 (66.3) | ||
| Mortality | ||||
| In-hospital | 17 (17.5) | 12 (12.6) | 0.42 | |
| 1 year | 31 (30.7) | 22 (23.2) | 0.25 |
Data shown as means±SD or number (percentage).
*Complications occurring before the involvement of the ET during the post-ET period.
†Renal failure requiring renal replacement therapy.
ET, endocarditis team; IE, infective endocarditis; TOE, transoesophageal echocardiogram; TTE, transthoracic echocardiogram.