Table 2

Three weeks stent-level optical coherence tomography (OCT) analysis

BMS (n=18) MSG (n=19) p Value
Quantitative findingsMinimum lumen area (mm2)4.4 (3.3–6.6)4.6 (3.7–5.7)0.68
NIH at minimum lumen area site (%)21.5 (9.7–30.4)20.3 (11.2–26.2)0.72
Minimum stent area (mm2)5.85 (4.3–6.9)5.5 (4.4–6.3)0.47
Proximal reference lumen area (mm2)6.5 (5.9–8.8)6.9 (5.0–8.3)0.72
Distal reference lumen area (mm2)6.2 (3.4–7.5)5.3 (4.3–7.5)0.69
Stent length by OCT (mm)18.4 (18.2–19.6)18.2 (17.8–22.6)0.52
Lumen area (mm3/mm)6.2 (3.9–7.8)5.7 (5.0–6.9)0.71
Stent area (mm3/mm)6.8 (5.4–8.0)6.3 (5.8–7.1)0.54
Neointimal thickness (stent level) (mm)0.095 (0.06–0.17)0.085 (0.07–0.12)0.81
Neointimal thickness (strut level) (mm)0.09 (0.04–0.17)0.07 (0.04–0.15)0.83
NIH area (mm3/mm)0.7 (0.3–1.3)0.6 (0.4–0.9)0.83
%NIH volume (=NIH/stent volume) (%)11.0 (3.9–21.5)8.9 (5,7–13.6)0.86
Strut level findingsTotal struts analysed198 (184–226)209 (195– 257)0.17
A. Definitely uncovered (%)0 (0–0)0 (0–0)0.97
B. Covered with fibrin (%)0 (0–0)0 (0–0)0.71
C. Partially covered (%)1.7 (0.4–4.6)2.83 (0.3–7.5)0.74
D. Covered-protruding (%)17.4 (3.5–41.7)18.68 (12.3–34.9)0.95
E. Covered-embedded (%)81.2 (49.8–95.5)74.21 (58.9–86.4)0.90
Fully uncovered (A+B) (%)0.0 (0.0–0.5)0.0 (0–0.5)0.94
Malapposed (%)0 (0–1.02)0 (0–2.6)0.80
Qualitative findingsHomogeneous NIH (%)76.5%72.2%1.00
Heterogeneous NIH (%)17.6%27.8%0.69
Layered NIH (%)5.9%0.0%0.49
NIH with macrophage (%)0 (0.0%)1 (5.3%)1.00
NIH with peri-strut microvessel (%)2 (11.1%)1 (5.3%)0.60
NIH with any thrombus (%)2 (11.8%)2 (10.5%)1.00
Any malapposition (%)7 (38.9%)8 (42.1%)0.84
Length of malapposition (mm) 2.4 (0.4–4.2)1.9 (1.4– 5.5)0.91
  • Median and IQR.

  • BMS, bare metal stent; MSG, microengineered stent grooves; NIH, neointimal hyperplasia.