Table 1

Clinical characteristics and echocardiographic findings in 80 healthy individuals, 100 HCM LVH− patients and 180 HCM LVH+ patients

Healthy individuals (n=80) HCM LVH− patients (n=100) HCM LVH+ patients (n=180) p Value
Age (years)54±1536±15* 53±17<0.001
Women, n (%)45 (56)61 (61)75 (42)*† <0.01
BMI (kg/m2)24±324±427±4*† <0.001
BSA (m2)1.9±0.21.8±0.21.9±0.2 <0.001
Heart rate (bpm)62±1068±14* 64±11 0.01
NYHA class (1–4)1.0±0.11.0±0.22.0±0.9*† <0.001
Systolic BP (mm Hg)124±11127±18131±120.27
Diastolic BP (mm Hg)71±1176±1079±130.09
 MWT (mm)9±18±119±4*† <0.001
 Peak LVOT gradient (mm Hg)4±15±231±4*† <0.001
 LVEDD (mm)51±549±4* 47±6*† <0.001
 LVESD (mm)33±531±4* 28±6*† <0.001
 IVSd (mm)8±28±216±4*† <0.001
 LVPWd8±28±310±3*† <0.001
 LV mass/BSA (g/m2)73±2271±15132±45*† <0.001
  • Values are represented as mean±SD.

  • p values are based on ANOVA and χ2 test.

  • *p<0.05 compared with healthy individuals.

  • †p<0.05 compared with HCM LVH− patients by Bonferroni post hoc correction.

  • ANOVA, analysis of variance; BMI, body mass index; BP, blood pressure; BPM, beats per minute; BSA, body surface area; HCM, hypertrophic cardiomyopathy; HCM LVH−, HCM patients without increased wall thickness; HCM LVH+, HCM patients with increased wall thickness; MWT, maximal wall thickness; NYHA class, New York Heart Association functional classification; LV, Left ventricular; LVEDD, left ventricular end-diastolic diameter; LVESD, left ventricular end-systolic diameter; LVH, left ventricular hypertrophy; LVOT, left ventricle outflow tract; LVPWd, left ventricular posterior wall diameter; IVSd, interventricular septum diameter.