Table 4

Cox regression analysis for all-cause mortality during long-term follow-up in the group of patients with STEMI who survived the first 30 days post-STEMI

UnivariateMultivariate
HR95% CIp ValueHR95% CIp Value
Gender (male)0.990.56 to 1.730.96
Age (years)1.071.04 to 1.09 <0.001 1.051.03 to 1.08 <0.001
Diabetes2.281.27 to 4.12 0.006 1.820.99 to 3.340.054
Hypercholesterolaemia* 0.460.20 to 1.060.07
Hypertension 1.200.74 to 1.960.46
Current smoker0.910.56 to 1.480.71
Family history of CAD0.570.33 to 0.97 0.04 0.750.43 to 1.320.32
Presenting in Killip class≥21.470.53 to 4.050.46
Culprit vessel
 Left main9.492.31 to 38.94 0.002 8.401.89 to 37.39 0.005
 RCA0.860.52 to 1.400.54
 LAD1.240.77 to 2.000.39
 LCx0.710.34 to 1.480.35
Three-vessel CAD1.951.21 to 3.16 0.006 1.340.80 to 2.230.26
eGFR ≤60 mL/min/1.73 m2 2.501.40 to 4.44 0.002 0.930.48 to 1.800.83
Peak cardiac troponin T level ≥3.5 µg/L1.310.79 to 2.170.30
LV ejection fraction ≤40%1.430.85 to 2.410.18
Medication at discharge
Beta-blocker0.750.30 to 1.870.54
Aspirin0.500.18 to 1.370.18
Clopidogrel20.280.00 to 4,6·107 0.69
ACE inhibitor/ARB0.760.24 to 2.420.64
Statin0.810.11 to 5.860.84
Incomplete revascularisation 1.911.14 to 3.20 0.01 1.530.89 to 2.610.12
  • ARB, angiotensin receptor blockers; eGFR, glomerular filtration rate estimated using the Cockroft-Gault formula; LAD, left anterior descending coronary artery; LCx, left circumflex coronary artery; LV, left ventricle; PCI, percutaneous coronary intervention; RCA, right coronary artery; STEMI, ST-segment elevation myocardial infarction.

  • * Serum total cholesterol ≥230 mg/dL and/or serum triglycerides ≥200 mg/dL or treatment with lipid-lowering drugs.

  • Defined as systolic blood pressure ≥140 mm Hg and/or diastolic blood pressure ≥90 mm Hg and/or the use of antihypertensive medication.

  • Complete revascularisation was defined as treating all present significant coronary artery stenosis ≥70% during primary PCI or before discharge.