Univariate | Multivariate | |||||
HR | 95% CI | p Value | HR | 95% CI | p Value | |
Gender (male) | 0.99 | 0.56 to 1.73 | 0.96 | |||
Age (years) | 1.07 | 1.04 to 1.09 | <0.001 | 1.05 | 1.03 to 1.08 | <0.001 |
Diabetes | 2.28 | 1.27 to 4.12 | 0.006 | 1.82 | 0.99 to 3.34 | 0.054 |
Hypercholesterolaemia* | 0.46 | 0.20 to 1.06 | 0.07 | |||
Hypertension† | 1.20 | 0.74 to 1.96 | 0.46 | |||
Current smoker | 0.91 | 0.56 to 1.48 | 0.71 | |||
Family history of CAD | 0.57 | 0.33 to 0.97 | 0.04 | 0.75 | 0.43 to 1.32 | 0.32 |
Presenting in Killip class≥2 | 1.47 | 0.53 to 4.05 | 0.46 | |||
Culprit vessel | ||||||
Left main | 9.49 | 2.31 to 38.94 | 0.002 | 8.40 | 1.89 to 37.39 | 0.005 |
RCA | 0.86 | 0.52 to 1.40 | 0.54 | |||
LAD | 1.24 | 0.77 to 2.00 | 0.39 | |||
LCx | 0.71 | 0.34 to 1.48 | 0.35 | |||
Three-vessel CAD | 1.95 | 1.21 to 3.16 | 0.006 | 1.34 | 0.80 to 2.23 | 0.26 |
eGFR ≤60 mL/min/1.73 m2 | 2.50 | 1.40 to 4.44 | 0.002 | 0.93 | 0.48 to 1.80 | 0.83 |
Peak cardiac troponin T level ≥3.5 µg/L | 1.31 | 0.79 to 2.17 | 0.30 | |||
LV ejection fraction ≤40% | 1.43 | 0.85 to 2.41 | 0.18 | |||
Medication at discharge | ||||||
Beta-blocker | 0.75 | 0.30 to 1.87 | 0.54 | |||
Aspirin | 0.50 | 0.18 to 1.37 | 0.18 | |||
Clopidogrel | 20.28 | 0.00 to 4,6·107 | 0.69 | |||
ACE inhibitor/ARB | 0.76 | 0.24 to 2.42 | 0.64 | |||
Statin | 0.81 | 0.11 to 5.86 | 0.84 | |||
Incomplete revascularisation‡ | 1.91 | 1.14 to 3.20 | 0.01 | 1.53 | 0.89 to 2.61 | 0.12 |
ARB, angiotensin receptor blockers; eGFR, glomerular filtration rate estimated using the Cockroft-Gault formula; LAD, left anterior descending coronary artery; LCx, left circumflex coronary artery; LV, left ventricle; PCI, percutaneous coronary intervention; RCA, right coronary artery; STEMI, ST-segment elevation myocardial infarction.
* Serum total cholesterol ≥230 mg/dL and/or serum triglycerides ≥200 mg/dL or treatment with lipid-lowering drugs.
† Defined as systolic blood pressure ≥140 mm Hg and/or diastolic blood pressure ≥90 mm Hg and/or the use of antihypertensive medication.
‡ Complete revascularisation was defined as treating all present significant coronary artery stenosis ≥70% during primary PCI or before discharge.