Echocardiographic parameters and systemic haemodynamics
| Baseline sea level | Hypoxia at rest | Hypoxia during exercise* | p Value | |
|---|---|---|---|---|
| RV end-diastolic diameter | ||||
| PAH | 41 (7)† | 40 (8)† | 40 (8)† | 0.87 |
| Control | 29 (8) | 22 (9) | 29 (8) | 0.20 |
| RV end-systolic area, cm2 | ||||
| PAH | 14 (6)† | 14 (7)† | 14 (8)† | 0.97 |
| Control | 8 (3) | 7 (2) | 6 (2) | 0.21 |
| RV:LV end-diastolic diameter ratio | ||||
| PAH | 1.01 (0.17)† | 1.05 (0.21)† | 1.04 (0.25)† | 0.85 |
| Control | 0.66 (0.14) | 0.64 (0.09) | 0.68 (0.14) | 0.79 |
| RV:LV end-diastolic area ratio | ||||
| PAH | 0.86 (0.39)† | 0.99 (0.40)† | 1.04 (0.40)† | 0.47 |
| Control | 0.43 (0.08) | 0.61 (0.15) | 0.51 (0.11) | 0.03 |
| RA end-systolic area, cm2 | ||||
| PAH | 18 (7) | 19 (8)† | 17 (7)† | 0.76 |
| Control | 12 (2) | 12 (2) | 11 (3) | 0.67 |
| LV EF % | ||||
| PAH | 62 (12) | 62 (11) | 68 (9) | 0.25 |
| Control | 65 (7) | 68 (7) | 76 (7) | 0.03 |
| HR, bpm | ||||
| PAH‡ | 76 (13)† | 78 (12)† | 94 (16) | 0.02 |
| Control | 62 (7) | 65 (8) | 88 (9) | 0.01 |
| SBP, mm Hg | ||||
| PAH‡ | 112 (11) | 117 (14) | 123 (18) | 0.33 |
| Control | 117 (15) | 124 (20) | 131 (20) | 0.66 |
Data presented as mean (SD). N=14 PAH, N=7 Control.
*N=11 PAH.
†versus Control unpaired t-test p<0.05.
‡N=9.
EF, ejection fraction; HR, heart rate; LV, left ventricular; RA, right arterial; RV, right ventricular; SBP, systolic blood pressure.