Patient demographics, baseline lung function and initial diagnostic values
| PAH | Control | p Value | |
|---|---|---|---|
| Male:female | 6:8 | 4:3 | – |
| Age, years | 61 (15) | 51 (15) | 0.17 |
| Height, cm | 167 (12) | 166 (9) | 0.78 |
| BMI | 27.7 (8.1) | 25.5 (3.5) | 0.51 |
| FEV1, L | 2.18 (0.98) | 3.36 (0.84) | 0.02 |
| Per cent predicted | 77 (16) | 109 (12) | |
| FVC, L | 2.93 (1.23) | 4.34 (0.96) | 0.03 |
| Per cent predicted | 81 (15) | 112 (10) | |
| KCO, mL.mm Hg.min.L | 3.3 (1.0) | 4.5 (0.9) | 0.04 |
| Per cent predicted | 59 (17) | 92 (10) | |
| VA, L | 4.53 (1.45) | 5.54 (0.72) | 0.01 |
| Per cent predicted | 79 (12) | 107 (14) | |
| Mean PPA, mm Hg | 37 (10) | – | |
| PVR, woods units | 4.9 (3.5) | – | |
| 6MWT, m | 391 (153) | – | |
| Per cent predicted | 74 (21) | – |
Data presented as mean (SD).
6MWT, 6 min walk test; BMI, body mass index; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; KCO, transfer factor for carbon monoxide corrected for VA; PAH, pulmonary arterial hypertension; PPA, pulmonary arterial pressure; PVR, pulmonary vascular resistance; VA, alveolar volume.