Patient characteristics recorded during the index admission (data are median (IQR) and number occurring (%))
| Variables | ACS-HIP | MI-HIP | MI-HInfoD | MI-MINAP | TnT +ve only | Any case (ACS, MI or TnT +ve) |
|---|---|---|---|---|---|---|
| N | 1439 | 704 | 544 | 203 | 823 | 2426 |
| Age (years) | 67 (58–77) | 69 (59–78) | 71 (60–80) | 65 (56–73) | 77 (69–84) | 72 (61–81) |
| Age >75—men | 181 (21%) | 113 (24%) | 95 (27%) | 18 (13%) | 211 (47%) | 440 (32%) |
| Age >75—women | 224 (38%) | 117 (49%) | 102 (54%) | 18 (29%) | 250 (67%) | 511 (50%) |
| Women | 591 (41%) | 241 (34%) | 189 (35%) | 63 (31%) | 375 (46%) | 1029 (42%) |
| TnT ≥0.03* µg/L | 724 (50%) [34] | 678 (98%) [13] | 510 (99%) [27] | 191 (96%) [4] | 823 | 1698 (71%) [51] |
| TnT >1.0* µg/L | 324 (23%) [34] | 323 (47%) [13] | 335 (65%) [27] | 163 (82%) [4] | 85 (10%) | 491 (21%) [51] |
| History of diabetes | 227 (16%) | 104 (15%) | n | n | 166 (20%) | n |
| History of MI | 246 (17%) | 103 (15%) | n | n | n | n |
| History of hypertension | 541 (38%) | 255 (36%) | n | n | n | n |
| Loop diuretic µg/L | 305 (21%) | 162 (23%) | n | 15 (12%) [81] | n | n |
| Aspirin | 1027 (71%) [2] | 517 (74%) [2] | n | 144 (97%) [55] | n | n |
| ACE inhibitor | 589 (41%) [1] | 374 (53%) [1] | n | 121 (92%) [71] | n | n |
| Angiotension receptor blocker | 82 (6%) [1] | 30 (4%) [1] | n | 2 (3%) [127] | n | n |
| β blocker | 873 (61%) [1] | 473 (67%) [1] | n | 120 (91%) [71] | n | n |
| Aldosterone antagonist | 59 (4%) [1] | 37 (5%) [1] | n | 5 (4%) [82] | n | n |
| Statin | 979 (68%) | 513 (73%) | n | 132 (95%) [64] | n | n |
| Report on LV function available | 703 [736] | 409 [295] | 293 [251] | 125 [78] | 298 [525] | 1055 [1371] |
| LVSD | 236 (34%) | 173 (42%) | 142 (48%) | 47 (38%) | 134 (45%) | 401 (38%) |
| Sodium | 139 (137–141) [18] | 139 (137–140) [2] | 139 (136–140) [3] | 138 (136–140) [1] | 138 (136–141) [8] | 139 (137–141) [27] |
| K | 4.3 (4–4.5) [71] | 4.3 (4–4.6) [23] | 4.3 (4–4.6) [24] | 4.2 (4–4.5) [8] | 4.3 (3.9–4.7) [43] | 4.3 (4.0–4.6) [122] |
| eGFR† | 69 (53–83) [18] | 64 (49–79) [2] | 64 (44–77) [3] | 69 (54–85) [1] | 48 (31–68) [11] | 62 (43–78) [33] |
| eGFR <60‡ | 473 (33%) | 279 (40%) | 230 (43%) [3] | 66 (33%) | 539 (66%) | 1109 (46%) |
| eGFR <30 | 94 (6.5%) | 67 (9.5%) | 66 (12.1%) | 9 (4.4%) | 191 (23%) | 321 (13%) |
| WCC | 8.6 (6.9–10.9) [28] | 9.9 (7.8–12.2) [10] | 10.7 (8.35–13.6) [13] | 10.6 (8.5–13.1) [2] | 10.7 (8.1–14.5) [21] | 9.3 (7.2–9.3) [55] |
| Diabetic | 252 (17.5%) | 119 (16.9%) | 83 (15.3%) | 24 (11.8%) | 166 (20%) | 443 (18%) |
| Anaemia in first available Hb§ | 333 (24%) [27] | 193 (28%) [10] | 165 (31%) [13] | 37 (18%) [2] | 451 (56%) [21] | 861 (36%) [57] |
| In-patient mortality | 87 (6%) | 78 (11%) | 104 (19%) | 10 (5%) | 209 (25%) | 342 (14%) |
| 30-day Mortality | 96 (7%) | 84 (12%) | 101 (19%) | 12 (6%) | 187 (23%) | 343 (14%) |
| One-year mortality | 179 (12%) | 134 (19%) | 149 (27%) | 19 (9%) | 334 (41%) | 597 (25%) |
| Overall mortality by end of 2008 | 301 (21%) | 203 (29%) | 202 (37%) | 29 (14%) | 472 (57%) | 877 (36%) |
| Overall mortality by June 2014 | 542 (38%) | 326 (46%) | 283 (52%) | 55 (27%) | 600 (73%) | 1269 (52%) |
[Numbers in italics in square brackets are numbers of patients with missing data].
Any case means a patient who belonged to any one of the other groups.
*Double-counting is possible because some patients had multiple admissions with a positive troponin, only some of which were identified as admissions with ACS.
†Four-variable formula derived from the modification of diet in renal disease study (4V MDRD), GFR=186×(Creat/88.4)−1.154×Age−0.203×0.742 if female ×1.212 if African Caribbean, was used to estimate the GFR.
‡eGFR <60 was defined as eGFR <60 mL/min/1.73 m2.
§Anaemia: WHO criteria for anaemia are used (man <13 g/dL and woman <12 g/dL).
ACS, acute coronary syndrome; any case, all ACS-HIP (MI and unstable angina in HIP), MI-HID, MI-MINAP and TnT +ve; eGFR, estimated glomerular filtration rate; GFR, glomerular filtration rate; HInfoD, Hospital Information Department; HIP, Hull Infarction Project; LVSD, left ventricular systolic dysfunction; MI, myocardial infarction; MINAP, Myocardial Infarction National Audit Project; TnT +ve, positive troponin T; WCC, white cell count.