Multivariable association of high-risk ECG with (1) sudden and (2) non-sudden coronary deaths in all 2167 men*
| Sudden death (n=184/2167) | Non-sudden cardiac death (n=78/2167) | |||||
|---|---|---|---|---|---|---|
| Adjusted HR | 95% CI | p Value | Adjusted HR | 95% CI | p Value | |
| ECG | ||||||
| Low risk | 1 | – | 0.001 | 1 | – | 0.21 |
| High risk | 1.94 | 1.31 to 2.88 | 0.55 | 0.22 to 1.40 | ||
| Peak flow rate (L/min) | ||||||
| <430 | 1.40 | 0.88 to 2.21 | 0.16† | 1.86 | 0.91 to 3.81 | 0.045† |
| 430 – <490 | 1.29 | 0.83 to 2.00 | 2.00 | 1.01 to 3.96 | ||
| 490 – <550 | 1.32 | 0.88 to 1.96 | 1.58 | 0.82 to 3.02 | ||
| ≥550 | 1 | – | 1 | – | ||
| Systolic blood pressure | ||||||
| Per 10 mm Hg increase | 1.10 | 1.04 to 1.17 | 0.002 | 1.17 | 1.07 to 1.29 | 0.001 |
| Body mass index | ||||||
| Per kg/m2 increase | 1.09 | 1.03 to 1.14 | 0.002 | 1.07 | 0.99 to 1.16 | 0.11 |
| Smoking status | ||||||
| Non-smoker | 1 | – | 0.037† | 1 | – | 0.22† |
| Ex-smoker | 1.36 | 0.83 to 2.21 | 0.69 | 0.33 to 1.42 | ||
| Current smoker | 1.65 | 1.02 to 2.68 | 1.31 | 0.67 to 2.55 | ||
| Previous angina | ||||||
| No | 1 | – | 0.034 | 1 | – | 0.23 |
| Yes | 1.79 | 1.04 to 3.06 | 1.74 | 0.71 to 4.27 | ||
| Cholesterol | ||||||
| Per mmol/L increase | 1.15 | 1.00 to 1.32 | 0.043 | 1.32 | 1.08 to 1.62 | 0.008 |
| Fibrinogen (g/L) | ||||||
| ≤3.5 | 1 | – | 0.007† | 1 | – | 0.025† |
| >3.5–4 | 1.47 | 0.99 to 2.18 | 1.68 | 0.92 to 3.06 | ||
| >4 | 1.86 | 1.09 to 3.15 | 2.11 | 0.93 to 4.78 | ||
| Factor VII (% of standard) | ||||||
| Per 10 unit increase | 1.05 | 1.00 to 1.11 | 0.071 | 1.01 | 0.92 to 1.10 | 0.83 |
*Also adjusted for current age, triglycerides, platelets, white cell count, red blood cell count, haemoglobin, packed cell volume, alcohol use, social class, factor V and factor VIII.
†Trend test.