Table 5

Cox regression model using clinical and echocardiographic variables

HR95% CIUnivariate
p Value
p Value
PASP ≥50 (mm Hg)*2.21.41 to 3.34<0.001<0.001
E/E ≥150.960.27 to 3.440.0340.948
JA/LAA ≥40%2.240.87 to 5.790.0230.128
RV ≥60 (mL/beat)1.090.12 to
EROA ≥40 (mm2)0.870.09 to 8.540.0290.917
LVEF <50 (%)2.830.79 to 10.20.0260.112
NYHA class ≥30.660.21 to 2.040.0850.466
Gender (male)1.230.43 to 3.530.7720.706
Age (years)1.041.00 to 1.020.0060.047
  • *p<0.05.

  • EF, ejection fraction; EROA, effective regurgitant orifice area; JA/LAA, ratio of jet area to left atrial area; LV, left ventricular; NYHA, New York Heart Association; PASP, pulmonary artery systolic pressure; RV, right ventricle; Rvol, regurgitant volume.