Clinical trials of invasive versus conservative management in patients with a non-ST segment elevation acute coronary syndrome, which included patients with prior CABG surgery
| Trials with CABG patients | Year published | Sample size, all participants | Sample size, participants with prior CABG | Prior CABG in invasive group | Prior CABG in conservative group | Minimum duration of follow-up for primary end point, months | Primary and secondary outcomes |
|---|---|---|---|---|---|---|---|
| VANQWISH22 | 1998 | 920 | 156 | 88 | 68 | 12 | Death and non-fatal MI |
| TRUCS23 | 2000 | 148 | 18 | 10 | 8 | 12 | Death and non-fatal MI |
| TACTICS-TIMI1810 24 | 2001 | 2220 | 484 | 243 | 241 | 6 | Death, non-fatal MI, rehospitalisation for acute coronary syndrome |
| ICTUS25 | 2005 | 1200 | 105 | 62 | 43 | 12 | Primary end point of death, non-fatal MI or rehospitalisation for anginal symptoms |
| CABG-ACS27 | After May 2014 | 60 | 60 | 31 | 29 | 18 | All-cause mortality, rehospitalisation for refractory ischaemia/angina, MI or heart failure |
| Total | 4548 | 823 (339) | 434 (191) | 389 (148) | – |
CABG-ACS, Coronary Artery Bypass Graft-Acute Coronary Syndrome; MI, myocardial infarction.