Logistic regression between awareness of hypertension at age 60–64 years and lifetime affective caseness variables (n=982)
| Aware vs unaware hypertensives (649 vs 333) | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cumulative lifetime affective caseness (OR (95% CI))* | Age-specific lifetime affective caseness (OR (95% CI))* | |||||||
| No symptoms (n=629) | Case-level symptoms at 1–2 time points (n=275) | Case-level symptoms at 3–4 time points (n=78) | p Value† | No symptoms (n=629) | Case-level symptoms only in the past (n=174) | Case-level symptoms at recent time (n=179) | p Value† | |
| Model 1 | 1.00 | 2.20 (1.60 to 3.05) | 1.78 (1.05 to 3.00) | <0.0001 | 1.00 | 1.94 (1.33 to 2.82) | 2.28 (1.55 to 3.55) | <0.0001 |
| Model 2 | 1.00 | 1.97 (1.40 to 2.76) | 1.45 (0.83 to 2.52) | 0.003 | 1.00 | 1.72 (1.16 to 2.55) | 1.93 (1.32 to 2.96) | 0.0005 |
| Model 3 | 1.00 | 1.90 (1.34 to 2.67) | 1.34 (0.76 to 2.36) | 0.001 | 1.00 | 1.66 (1.11 to 2.48) | 1.87 (1.24 to 2.82) | 0.002 |
| Model 4 | 1.00 | 1.91 (1.34 to 2.72) | 1.55 (0.86 to 2.78) | 0.001 | 1.00 | 1.67 (1.10 to 2.53) | 2.00 (1.30 to 3.06) | 0.001 |
Aware hypertensives=patients with both clinically ascertained and self-reported hypertension.
Unaware hypertensives=patients with clinically ascertained hypertension but not self-reported hypertension.
Model 1: unadjusted logistic regression.
Model 2: logistic regression adjusted for gender, body mass index (BMI) at age 60–64 years, educational attainment by age 26 years, socioeconomic position at age 53 years, history of cardiovascular disease (CVD) and diabetes mellitus status at age 60–64 years.
Model 3: model 2 additionally adjusted for covariates at age 60–64 years: heart rate, current smoking, alcohol consumption, physical activity and antidepressant treatment.
Model 4: model 3 additionally adjusted for duration of clinically ascertained hypertension in years from age 36 years.
*Affective caseness assessed at each time point as follow: Present State Examination-Index of Definition (PSE-ID) ≥5 at age 36, total Psychiatric Symptom Frequency (PSF) score ≥23 at age 43, and total General Health Questionnaire–28-items (GHQ-28) score ≥5 at ages 53 and 60–64 years.
†p Value for trend.