Case of affective symptoms at age 60–64 years vs non-case (127 vs 628)* | ||||
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Awareness of HT at age 53 years by antihypertensive treatment status (OR (95% CI)) | ||||
Predictor | Unaware (n=460) | Aware treated (n=212) | Aware untreated (n=83) | p Value† |
Model 1 | 1.00 | 2.33 (1.53 to 3.56) | 2.49 (1.41 to 4.41) | <0.0001 |
Model 2 | 1.00 | 1.86 (1.71 to 2.97) | 2.40 (1.34 to 4.29) | 0.003 |
Model 3 | 1.00 | 1.69 (1.04 to 2.74) | 2.40 (1.32 to 4.36) | 0.007 |
Unaware hypertensives=patients with clinically ascertained but not self-reported HT.
Aware treated hypertensives=patients with antihypertensive treatment with both clinically ascertained and self-reported HT.
Aware untreated hypertensives=patients without antihypertensive treatment with both clinically ascertained and self-reported HT.
Model 1: unadjusted logistic regression.
Model 2: logistic regression adjusted for gender, BMI at age 53 years, educational attainment by age 26 years, socioeconomic position at age 53 years and the following covariates at age 53 years: history of CVD and diabetes mellitus status, heart rate and lifestyle behaviours.
Model 3: model 2 additionally adjusted for affective symptoms at age 53 years.
*Affective caseness assessed as total GHQ-28 score ≥5.
†p Value for trend.
BMI, body mass index; CVD, cardiovascular disease; GHQ-28, General Health Questionnaire–28-items; HT, hypertension.