Tested population | Propensity score-matched population | |||||
---|---|---|---|---|---|---|
Tested—post heart surgery population (N=361) | Healthy controls (N=215) | p Value | Tested—post heart surgery population (N=167) | Healthy controls (N=167) | p Value | |
Caucasian race* | 343 (95.01) | 211 (98.14) | 0.058 | 162 (97.01) | 164 (98.20) | 0.474 |
Exclusive European* | 330 (91.41) | 201 (93.49) | 0.369 | 160 (95.81) | 156 (93.41) | 0.332 |
Exclusive Dutch language* | 296 (81.99) | 186 (86.51) | 0.155 | 144 (86.23) | 142 (85.03) | 0.755 |
Male sex* | 205 (56.79) | 93 (43.26) | 0.001 | 81 (48.50) | 81 (48.50) | 1.000 |
Age at randomisation, years† | 0.76 (0.22–4.1) | NA | NA | 2.11 (0.34–4.77) | NA | NA |
Type of congenital heart disease* | ||||||
Obstructive pathology | 79 (21.88) | NA | NA | 37 (22.15) | NA | NA |
Left-right shunt | 121 (33.51) | NA | NA | 60 (35.92) | NA | NA |
Cyanotic and not univentricular | 122 (33.79) | NA | NA | 59 (35.32) | NA | NA |
Cyanotic and univentricular | 70 (19.39) | NA | NA | 27 (16.16) | NA | NA |
Other | 11 (3.04) | NA | NA | 5 (2.99) | NA | NA |
RACHS classification* | ||||||
1 or 2 | 168 (47.72) | NA | NA | 79 (48.17) | NA | NA |
3 or 4 | 175 (49.71) | NA | NA | 84 (51.21) | NA | NA |
5 or 6 | 9 (2.55) | NA | NA | 1 (0.60) | NA | NA |
Syndrome, at randomisation* | 69 (19.11) | 16 (7.44) | <0.001 | 20 (11.98) | 16 (9.58) | 0.480 |
PELOD first 24 h in ICU† | 11 (2–12) | NA | NA | 11 (2–12) | NA | NA |
Socioeconomic status score† | 35 (24–48.5) | 42.5 (29–54) | <0.001 | 39.5 (29–50) | 39.5 (29–52.5) | 0.455 |
At follow-up† | ||||||
Height, cm | 107 (103–126) | 122 (108–151) | <0.001 | 116 (104–131) | 117 (107–139) | 0.069 |
Weight, kg | 18 (15–24) | 22 (18–40) | <0.001 | 20 (16–29) | 21 (18–34) | 0.072 |
Head circumference, cm | 50.7 (49.2–52.5) | 52 (50.8–54) | <0.001 | 51 (49.5–53) | 51.8 (50.5–53.4) | 0.001 |
Age, year | 4.67 (4.14–7.93) | 6.75 (4.68–11.56) | <0.001 | 6.02 (4.21–8.78) | 5.91 (4.58–9.07) | 0.359 |
*Numbers and percentages.
†Median (IQR).
ICU, intensive care unit; LGC, Leuven glucose control; NA, not applicable; PELOD, paediatric logistic organ dysfunction;43 RACHS, risk adjustment for congenital heart surgery.42