Baseline patient characteristics
| Total | RXT | NRXT | ||
|---|---|---|---|---|
| Variable | (n=198) | (n=19) | (n=179) | p Value |
| Age (years) | 81.1±8.4 | 68.3±11.7 | 82.5±6.6 | <0.00001 |
| Women | 90 (45.4%) | 12 (63.2%) | 78 (43.6%) | 0.1 |
| Body mass index (kg/m2) | 27±5.6 | 25.9±5.1 | 27.1±5.7 | 0.37 |
| NYHA 3 or 4 (%) | 169 (85.3%) | 14 (73.6%) | 155 (86.6%) | 0.17 |
| Peripheral artery disease | 62 (31.3%) | 2 (10.5%) | 60 (33.5%) | 0.04 |
| Previous heart failure | 105 (53.0%) | 8 (42.1%) | 97 (54.1%) | 0.32 |
| Coronary artery disease | 113 (57.1%) | 9 (47.3%) | 104 (58.1%) | 0.37 |
| Previous cerebrovascular event | 11 (5.6%) | 0 (0%) | 11 (6.1%) | 0.6 |
| Diabetes mellitus | 57 (28.8%) | 1 (5.3%) | 56 (31.3%) | 0.017 |
| Hypertension | 148 (74.7%) | 9 (47.3%) | 139 (77.6%) | 0.0095 |
| Chronic pulmonary disease | 75 (37.9%) | 9 (47.3%) | 66 (36.9%) | 0.37 |
| Logistic Euroscore (%) | 20.3±12.7 | 7.1±4.5 | 21.8±12.5 | <0.00 001 |
| Estimated glomerular filtration rate (mL/min) with Cockroft formula | 57.7±32.5 | 107.2±35.2 | 52.4±27.4 | <0.00001 |
| Previous cardiac surgery | 53 (26.8%) | 2 (10.5%) | 51 (28.5%) | 0.093 |
| Hostile thorax | 61 (30.1%) | 10 (52.6%) | 51 (28.5%) | 0.03 |
| Porcelain aorta | 31 (15.7%) | 12 (63.2%) | 19 (10.6%) | <0.00001 |
| History of atrial fibrillation | 73 (36.9%) | 2 (10.5%) | 71 (39.7%) | 0.012 |
| Pacemaker | 41 (20.7%) | 4 (21%) | 37 (20.6%) | 1 |
Values are expressed as mean±SD or n (%).
NRXT, non-radiation-induced valvular disease; NYHA, New York Heart Association; RXT, radiation-induced valvular disease.