Baseline demographic characteristics of the patients with a preserved LVEF >40% and with an impaired LVEF (≤40%)
| Preserved LVEF (n=448) | Impaired LVEF (n=262) | p Value | |
|---|---|---|---|
| Age (years, mean±SD) | 59.7±10.9 | 62.8±10.4 | <0.001 |
| Gender (n, %) | |||
| Male | 345 (77.0) | 194 (74.0) | 0.373 |
| Female | 103 (23.0) | 68 (26.0) | |
| BMI (kg/m2, mean±SD) | 27.7±3.7 | 27.8±4.3 | 0.663 |
| History of | |||
| Diabetes mellitus (n, %) | 64 (14.6) | 66 (26.6) | <0.001 |
| Treated hypercholesterolaemia (n, %) | 88 (27.5) | 52 (27.4) | 0.974 |
| Treated hypertension (n, %) | 268 (62.9) | 166 (66.4) | 0.361 |
| Myocardial infarction (n, %) | 67 (15.0) | 65 (25.3) | 0.001 |
| Angina pectoris (n, %) | 150 (33.6) | 112 (42.9) | 0.014 |
| Congestive heart failure (n, %) | 16 (3.6) | 32 (12.5) | <0.001 |
| Prior PTCA (%) | 22 (4.9) | 17 (6.5) | 0.373 |
| Prior CABG (%) | 6 (1.3) | 6 (2.3) | 0.343 |
| Killip class (n, %) | |||
| I | 144 (32.1) | 91 (34.7) | 0.299 |
| II | 283 (63.2) | 154 (58.8) | |
| III | 19 (4.2) | 17 (6.5) | |
| IV | 2 (0.4) | 0 (0.0) | |
| Infarct location (n, %) | |||
| Anterior | 212 (47.3) | 167 (64.0) | <0.001 |
| Posterior | 38 (8.5) | 15 (5.7) | |
| Lateral | 35 (7.8) | 16 (6.1) | |
| Inferoposterior | 109 (24.3) | 28 (10.7) | |
| Others | 54 (12.1) | 35 (13.4) | |
| PTCA performed at entry (n, %) | 149 (33.3) | 62 (23.8) | 0.008 |
| Thrombolytic therapy performed at entry (n, %) | 171 (38.2) | 101 (38.5) | 0.920 |
| Type of thrombolytic therapy (n, %) | |||
| Streptokinase | 69 (40.4) | 46(45.5) | 0.234 |
| Alteplase | 29 (17.0) | 10 (9.9) | |
| Tenecteplase | 47 (27.5) | 30 (29.7) | |
| Reteplase | 7 (4.1) | 8 (7.9) | |
| Other | 19 (11.1) | 7 (6.9) | |
| Estimated GFR (mL/min, mean±SD) | 89.4±34.3 | 82.9±30.5 | 0.015 |
| NT-proBNP (pg/mL, mean±SD) | 1601±2485 | 2809±3896 | <0.001 |
| SBP (mm Hg, mean±SD) | 139.3±23.4 | 140.8±225.0 | 0.433 |
| DBP (mm Hg, mean±SD) | 82.4±13.5 | 83.9±13.7 | 0.155 |
| HR (bpm, mean±SD) | 78.0±15.6 | 82.5±17.9 | <0.001 |
BMI, body mass index; CABG, coronary artery bypass graft; DBP, diastolic blood pressure; GFR, glomerular filtration rate (estimated by Cockroft-Gault formula); HR, heart rate; LVEF, left ventricular ejection fraction; NT-proBNP, N terminal pro-brain natriuretic peptide; PTCA, percutaneous transluminal coronary angioplasty; SBP, systolic blood pressure.