Clinical and biochemical characteristics, and their correlation with calibrated integrated backscatter in 29 men and 11 women with coronary artery disease
| Variable | Mean±SD or median (IQR) (n=40) | r | p Value |
|---|---|---|---|
| Age (years) | 65±11 | 0.31 | 0.053 |
| Weight (kg) | 83±13 | 0.003 | 0.99 |
| Height (cm) | 168±10 | −0.05 | 0.75 |
| Body surface area (m2) | 1.9±0.2 | −0.01 | 0.94 |
| Body mass index (kg/m2) | 30±6 | 0.02 | 0.90 |
| Systolic blood pressure (mm Hg) | 134±15 | 0.06 | 0.72 |
| Diastolic blood pressure (mm Hg) | 76±8 | 0.04 | 0.83 |
| Pulse pressure (mm Hg) | 58±14 | 0.04 | 0.80 |
| Fasting plasma glucose (mmol/L) | 6.0 (5.4–6.5)* | −0.10† | 0.53† |
| Fasting plasma insulin (pmol/L) | 65 (36–108)* | 0.02† | 0.93† |
| β-cell function from HOMA2-%B | 64 (52–110)* | 0.08† | 0.61† |
| Insulin sensitivity from HOMA2-%S | 84 (51–139)* | −0.008† | 0.96† |
| Insulin resistance from HOMA2-IR | 1.2 (0.8–2.0)* | 0.004† | 0.98† |
| Plasma NT-proBNP (pmol/L) | 16 (7–32)* | 0.34† | 0.03† |
| Plasma creatinine (μmol/L) | 87 (77–110)* | 0.33† | 0.04† |
| eGFR (mL/min/1.73 m2) | 68±16 | −0.33 | 0.04 |
| Plasma C reactive protein (mg/L) | 2.8 (0.7–7.2)* | 0.03† | 0.87† |
| Plasma PIP (μg/L) | 284±78 | 0.07 | 0.68 |
| Plasma PINP (μg/L) | 32±14 | 0.01 | 0.95 |
| Plasma PIIINP (μg/L) | 2.5±1.1 | 0.03 | 0.84 |
eGFR is calculated from the Modification of Diet in Renal Disease formula.29
HOMA2-%B; HOMA2-%S and HOMA2-IR were calculated using the HOMA calculator V.2.2.30
*Median value and IQR given non-parametric distribution.
†Values derived from log-transformed data.
eGFR, estimated glomerular filtration rate; HOMA2-%B, β-cell function; HOMA2-IR, insulin resistance; HOMA2-%S, insulin sensitivity; NT-proBNP, amino-terminal-pro-B-type natriuretic peptide; PIIINP, intact amino-terminal propeptide of type III procollagen; PINP, intact amino-terminal propeptide of type 1 procollagen; PIP, carboxy-terminal propeptide of procollagen type I.