Accuracy of the BRS for major bleeding by categories of BMI
| BRS category | Low BMI | High BMI | Significant |
|---|---|---|---|
| Low risk | 13/612 (2.1) | 62/3170 (1.9) | 0.89 |
| High risk | 18/230 (7.8) | 50/603 (8.3) | 0.47 |
| All risk | 31/842 (3.7) | 112/3773 (2.9) | 0.05 |
| Test discrimination | Sensitivity 0.58 Specificity 0.74 PPV: 8% NPV: 98% +LR: 2.2 (CI 1.6 to 3.1) −LR: 0.5 (CI 0.3 to 0.9) | Sensitivity 0.45 Specificity 0.84 PPV: 8% NPV: 98% +LR: 2.9 (CI 2.4 to 3.7) −LR: 0.6 (CI 0.5 to 0.8) |
BMI, body mass index; BRS, Bleeding Risk Score; LR−, negative Likelihood Ratio; LR+, positive Likelihood Ratio; NPV, negative predictive value; PPV, positive predictive value.