Major cardiovascular event rates and HRs according to quartiles of baseline hsCRP in the whole cohort as well as in patients with increasing or decreasing hsCRP
| Baseline hsCRP | One-year changes in hsCRP from baseline | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Increase | Decrease | ||||||||
| Quartiles of baseline hsCRP | N | HR | Events per 1000 patient-years | N | HR | Events per 1000 patient-years | N | HR | Events per 1000 patient-years |
| 1st quartile | 422 | 1 | 83 | 171 | 1 | 92 | 231 | 1 | 75 |
| 2nd quartile | 412 | 1.1 (0.87 to 1.39) | 95 | 143 | 1.2 (0.84 to 1.71) | 119 | 232 | 1.03 (0.73 to 1.44) | 78 |
| 3rd quartile | 388 | 1.28 (1.02 to 1.62)* | 116 | 85 | 1.31 (0.87 to 1.96) | 134 | 258 | 1.28 (0.94 to 1.75) | 102 |
| 4th quartile | 396 | 1.19 (0.94 to 1.51) | 106 | 74 | 1.62 (1.09 to 2.4)* | 168 | 280 | 1.07 (0.78 to 1.47) | 82 |
| 1st–3rd quartile | 1222 | 1.06 (0.88 to 1.28) | 399 | 1.06 (0.88 to 1.28)* | 721 | 0.96 (0.75 to 1.23) | |||
*p<0.05.
hsCRP, high-sensitivity C reactive protein.