Performance of MCE risk models including traditional risk factors with and without hsCRP
| C-index | (95% CI) | p Value | NRI | (95% CI) | IDI | (95% CI) | p Value | |
|---|---|---|---|---|---|---|---|---|
| Basic model | 0.57 | (0.43 to 0.71) | ||||||
| Basic model+baseline hsCRP and 1-year changes | 0.60 | (0.41 to 0.79) | <0.05 | 0.24 | (0.13 to 0.38) | 0.03 | (0 to 0.07) | 0.07 |
Basic model: age, sex, heart rate, white cell count, tobacco and treatment group.
hsCRP, high-sensitivity C reactive protein; IDI, integrated discrimination improvement; MCE, major cardiovascular event; NRI, net reclassification improvement.