Clinical characteristics of the study population
| AS | Control | p Value | |
|---|---|---|---|
| Number | 101 | 26 | |
| Age (year) | 76±8 | 71±9 | <0.005 |
| Gender (male/female) | 51/50 | 17/9 | 0.17 |
| BSA (/m2) | 1.52±0.18 | 1.59±0.17 | 0.1 |
| HR (bpm) | 74±16 | 72±16 | 0.59 |
| SBP (mm Hg) | 153±22 | 140±22 | <0.05 |
| DBP (mm Hg) | 78±13 | 78±15 | 0.96 |
| Risk factors | |||
| Hypertension (%) | 84 (83%) | 13 (50%) | <0.001 |
| Diabetes (%) | 32 (32%) | 5 (19%) | 0.21 |
| Hypercholesterolaemia (%) | 50 (50%) | 9 (35%) | 0.17 |
| eGFR (mL/min/1.73 m2) | 52±33 | 77±22 | <0.001 |
| Left chamber volumes and EF | |||
| LVEDV (mL) | 88±20 | 74±10 | 0.001 |
| LVESV (mL) | 35±16 | 21±7 | <0.001 |
| LVEF (%) | 62±10 | 72±6 | <0.001 |
| SV (mL) | 53±10 | 53±5 | 0.9 |
| LA volume (mL) | 75±23 | 39±12 | <0.001 |
| Aortic valve | |||
| AVA (cm2) | 0.84±0.16 | 2.58±0.53 | <0.001 |
AS, aortic stenosis; AVA, aortic valve area; BSA, body surface area; DBP, diastolic blood pressure; eGFR, estimated-glomerular filtration rate; HR, heart rate; LA, left atrial; LVEDV, left ventricular end-diastolic volume; LVEF, left ventricular ejection fraction; LVESV, left ventricular end-systolic volume; SBP, systolic blood pressure; SV, stroke volume.