Baseline characteristics for ADVANCE and PARTNER-B medical management
| ADVANCE | PARTNER-B | p Values (ADVANCE vs PARTNER-B) | |||
|---|---|---|---|---|---|
| All patients | High-risk cohort (EuroSCORE>20%) | Medical management | All patients | High-risk cohort | |
| N | 1015 | 369 | 179 | ||
| Mean age in years (±SD) | 81.1±6.4 | 82.7±5.7 | 83.0±8.0 | 0.001 | 0.614 |
| Male (%) | 49.4 | 49.9 | 46.9 | 0.537 | 0.510 |
| Logistic EuroSCORE, % (±SD) | 19.4±12.3 | 32.3±11.0 | 30.4±19.1 | <0.001 | 0.141 |
| NYHA III/IV (%) | 79.6 | 84.6 | 93.9 | <0.001 | 0.002 |
| Diabetes (%) | 31.3 | 27.1 | Not reported | NA | NA |
| Coronary artery disease (%) | 57.6 | 66.1 | 74.3 | <0.001 | 0.052 |
| Peripheral vascular disease (%) | 19.5 | 27.1 | 25.1 | 0.086 | 0.617 |
| Atrial fibrillation (%) | 32.9 | 36.8 | 48.8 | <0.001 | 0.005 |
| Cerebrovascular disease (%) | 12.9 | 17.6 | 27.5 | <0.001 | 0.007 |
| Prior MI (%) | 16.0 | 22.0 | 26.4 | 0.001 | 0.289 |
| Prior PCI (%) | 31.1 | 36.0 | 24.8 | 0.090 | 0.009 |
| Prior CABG (%) | 21.4 | 34.7 | 45.6 | <0.001 | 0.014 |
| Prior permanent pacemaker (%) | 12.9 | 16.5 | 19.5 | 0.017 | 0.384 |
CABG, coronary artery bypass graft; MI, myocardial infarction; NYHA, New York Heart Association; PCI, percutaneous coronary intervention.