Non-COPD | COPD | p Value | |
---|---|---|---|
Number of patients | 76 324 (94.0) | 4867 (6.0) | |
Age | 70±13 | 75±9 | <0.001 |
Female gender | 27 466 (36.0) | 2239 (46.0) | <0.001 |
Body mass index (n=55 516) | 26.7±4.7 | 25.4±5.4 | <0.001 |
Smoking status (n=80 879) | <0.001 | ||
Current smoker | 16 522 (21.7) | 1596 (32.9) | |
Ex–smoker | 20 791 (27.3) | 2222 (45.9) | |
Never smoked | 31 850 (41.9) | 681 (14.1) | |
Unknown | 6872 (9.0) | 345 (7.1) | |
Comorbidities | |||
Previous MI | 5990 (7.8) | 665 (13.7) | <0.001 |
Previous stroke | 6904 (9.0) | 650 (13.4) | <0.001 |
Heart failure | 4836 (6.3) | 983 (20.2) | <0.001 |
Renal failure | 1478 (1.9) | 231 (4.7) | <0.001 |
Hypertension | 14 848 (19.5) | 1537 (31.6) | <0.001 |
Diabetes | 14 613 (19.1) | 999 (20.5) | 0.018 |
Peripheral artery disease | 3121 (4.1) | 498 (10.2) | <0.001 |
Cancer | 1638 (2.1) | 258 (5.3) | <0.001 |
Previous bleeding | 3541 (4.6) | 428 (8.8) | <0.001 |
Prior CABG | 2625 (3.4) | 208 (4.3) | 0.002 |
Prior PCI | 1548 (2.0) | 127 (2.6) | 0.006 |
Prior medication before MI | |||
ACE inhibitor | 12 216 (16.0) | 967 (19.9) | <0.001 |
Angiotensin II receptor blocker | 7894 (10.5) | 580 (12.1) | <0.001 |
Aspirin | 23 023 (30.2) | 1913 (39.3) | <0.001 |
Clopidogrel | 2603 (3.4) | 217 (4.5) | <0.001 |
β-blocker | 23 315 (30.6) | 1544 (31.7) | 0.161 |
Calcium channel blocker | 11 615 (15.2) | 878 (18.0) | <0.001 |
Digitalis | 1918 (2.5) | 290 (6.0) | <0.001 |
Diuretic | 17 170 (22.5) | 1910 (39.2) | <0.001 |
Statin | 14 452 (18.9) | 1069 (22.0) | <0.001 |
Nitrate | 6331 (8.3) | 630 (12.9) | <0.001 |
Warfarin | 2816 (3.7) | 275 (5.7) | <0.001 |
The mean and SD are presented for continuous variables and count and percentage for categorical variables.
CABG, coronary arterial bypass graft surgery; COPD, chronic obstructive pulmonary disease; MI, myocardial infarction; PCI, percutaneous coronary intervention.