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Original research article
Did the use of the Guideliner V2TM guide catheter extension increase complications? A review of the incidence of complications related to the use of the V2 catheter, the influence of right brachiocephalic arterial anatomy and the redesign of the V3TM Guideliner and clinical outcomes
  1. Mohammad Alkhalil1,
  2. Alison Smyth1,
  3. Simon J Walsh1,
  4. Conor McQuillan2,
  5. Mark S Spence2,
  6. Colum G Owens2 and
  7. Colm G Hanratty1
  1. 1Cardiology Department, Belfast City Hospital, Belfast, UK
  2. 2Cardiology Department, Royal Victoria Hospital, Belfast, UK
  1. Correspondence to Dr Colm G Hanratty; Colm.hanratty{at}


Objective We sought to investigate the incidence of complications associated with V2 Guideliner, understand the mechanisms and evaluate the impact of alterations made to the V3 Guideliner.

Methods Retrospective analysis of consecutive cases employing V2 Guideliner from two university teaching hospitals. Complications were identified, analysed and classified into major versus minor ones. To understand the potential anatomical mechanism of these complications, analysis of normal great vessel anatomy was undertaken in separate cohort of patients undergoing cardiac catheterisation via right radial approach. Further analysis of consecutive cases employing V3 Gudieliner took place and the incidence of complications were compared between V2 and V3 groups.

Results Total of 188 cases of V2 Guideliner use were identified. One major complication was reported (coronary dissection). Proximal collar interaction and stent damage occurred in 19 cases (10%). Anatomical data suggest that extending the V2 Guideliner tubing sited the proximal collar of the device in the brachiocephalic/subclavian artery, a potential site of tortuosity and potential cause of the Guideliner proximal collar-stent interaction. Further analysis of 124 cases of V3 Guideliner use demonstrated no cases with proximal collar-stent interactions, one case of longitudinal stent deformation and two incidents of stent interaction with the distal edge of the V3 Guideliner.

Conclusions We have demonstrated a higher incidence of V2 Guideliner complications compared to previous series. The change in design of the V2 Guideliner was a likely contributor but the modifications with V3 Guideliner appear to have ameliorated this issue.

Statistics from

  • Received August 28, 2015.
  • Revision received October 17, 2015.
  • Accepted December 5, 2015.
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